You can edit the /etc/fstab or setup systemd mounts so all the files are mounted at the correct spot at startup. Different drives are mounted to folders on Linux instead of drive letters like on windows. Before you reboot, make sure everything works by running mount -a otherwise you will have to rescue the system
I want to try alpine out but the lack of systemd support is a blocker since I don’t want to add openrc support to all my Ansible playbooks that rely on systemd services and timers