FIT CTU Prague student, Android developer, and technology enthusiast.
I used to have an USB stick with Ubundu on it, so I see no reason that it shouldn’t be possible. But idk how drivers would work.
Also I would check how much RAM is needed to boot the live ISO (not during the process). If it is low enough, you can use swap.
Git projects and system configs are on GitHub (see etckeeper), the reset is synced to my self-hosted Nextcloud instance using their desktop client. There I have periodic backup using Borg for both the files and Nextcloud database.
Shut up and take my money!